ศ.นพ. อนันต์ ศรีเกียรติขจร

Print

 

   ศ.นพ. อนันต์ ศรีเกียรติขจร 

   Prof. Anan Srikiatkhachorn




ตำแหน่งทางวิชาการ: ศาสตราจารย์

โทรศัพท์: 662-256-4267 ต่อ 113

อีเมล: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

คุณวุฒิ:

  • 1978-1982 B.Sc. (Medical Science), Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

  • 1982-1984 M.D. (Hons), Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

  • 1987-1990 Diplomate Board of Neurology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

  • 1994-1995 Visiting Research Fellow, Institute of Neurological Sciences, The Prince Henry and Prince of Wales Hospitals, University of New South Wales, Sydney, Australia

  • 1998-2000 MSc. (Clincal Epidemiology) Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand


Professional Experiences:

  • 1990-1992 Lecturer, Neuro- and Behavioral Biology Center, Institute of Science and Technology for Development, Mahidol University

  • 1992-1994 Assistant Professor (Neurosciences), Neuro- and Behavioral Biology Center, Institute of Science and Technology for Development, Mahidol University

  • 1995-1996 Assistant Professor, Department of Physiology, Faculty of Medicine, Chulalongkorn University

  • 1996-2002 Associate Professor

  • 2002-present Professor (Neurosciences)

 

ความสนใจเฉพาะ:

  • Clinical and biological aspects of headache

 

ผลงานทางวิชาการ:

  • บทความวิจัย

  1. Srikiatkhachorn A. Migraine: the pathogenesis. J Neurol Soc Thai 1989;6:7-14. (Review articles)

  2. Srikiatkhachorn A, Phanthumchinda K. Spasticity.  Chula Med J 1989;34:311-22. (Review articles)

  3. Srikiatkhachorn A.  Platelet, serotonin and migraine.  Chula Med J 1991;35:605-14. (Review articles)

  4. Srikiatkhachorn A.  Epidemiology of headache in the Thai elderly: a study in Bangkae Home for the Aged.  Headache 1991;31:677-81.

  5. Phanthumchinda K, Srikiatkhachorn A.  Spinocerebellar degeneration.  J Med Assoc Thai  1991;74:71-9

  6. Khaoropthum S, Phanthumchinda K, Srikiatkhachorn A.  Successful surgical removal of intrinsic medullary vascular malformation: a case presentation.  J Med Assoc Thai1991;74:344-7.

  7. Limthavon C, Srikiatkhachorn A, Kotchabhakdi N, Govitrapong P.  Age-related changes in 5-HT2 serotonin receptor on human platelets. Thai J Pharmacol 1991;13:57-73.

  8. Srikiatkhachorn A, Phanthumchinda K.  Headache in an out-patient department. Chula Med J 1992;36:701-13.

  9. Govitrapong P, Limthavon C, Srikiatkhachorn A.  5-HT2 Serotonin receptor on platelet membrane of migraine patients.  Headache 1992;32:480-4.

  10. Kangsanarak A, Srikiatkhachorn A, Kotchabhakdi N.  Headache types in the elderly: an evaluation of behavioural risk factors. Bull Dep Med Serv 1992;17:453-60.

  11. Srikiatkhachorn A, Govitrapong P, Limthavon C. Up-regulation of 5-HT2 serotonin receptor: a possible mechanism of transformed migraine. Headache. 1994 Jan;34(1):8-11.

  12. Srisawat R, Srikiatkhachorn A, Kotchabhakdi N, Meksuriyen D.  Optimization of ion-pair high performance liquid chromatography for seperation of endogenous amines and their metabolites in rat brain tissue. Thai J Pharm Sci  1994;18:118-34

  13. Srikiatkhachorn A. Trigeminovascular system: the nociceptive system of cranial vessels.Chula Med J 1995;39:299-320. (Review articles)

  14. Srikiatkhachorn AAnthony M. Serotonin receptor adaptation in patients with analgesic induced headache. Cephalalgia. 1996 Oct;16(6):419-22.

  15. Srikiatkhachorn A, Anthony M. Platelet serotonin in patients with analgesic induced headache. Cephalalgia. 1996 Oct;16(6):423-26.

  16. Dumrongphol H, Srikiatkhachorn A, Hemachudha T, Kotchabhakdi N, Govitrapong P. Alteration of muscarinic acetylcholine receptors in rabies infected-dog brain. J Neurol Sci. 1996 Apr;137(1):1-6.

  17. Yang M, Srikiatkhachorn A, Anthony M, Chesterman CN, Chong BH. Serotonin uptake, storage and metabolism in megakaryoblasts. Int J Hematol. 1996 Feb;63(2):137-42.

  18. Yang M, Srikiatkhachorn A, Anthony M, Chong BH. Serotonin stimulates megakaryocyto-poiesis via 5HT2 receptor. Blood Coagul Fibrinolysis. 1996 Mar;7(2):127-33

  19. Jitapunkul S, Lailert C, Worakul P, Srikiatkhachorn A, Ebrahim S. Chula Mental Test: a screening test for elderly people in less developed countries. Int J Geriatr Psychiat 1996 Aug;11(8):715-20.

  20. Puangniyom S, Srikiatkhachorn A, Kotchabhakdi N, Govitrapong P. Alteration of 5-HT2 serotonin receptor in migraine patients with analgesic overuse. Chula Med J 1996;40:557-66.

  21. Srikiatkhachorn A, Phanthumchinda K. Prevalence and clinical features of chronic daily headache in a headache clinic. Headache 1997 May;37(5):277-80.

  22. Tarasub N, Srikiatkhachorn A, Govitrapong P. Effect of paracetamol on central 5-HT2A serotonin receptor. Chula Med J 1997;41:877-88.

  23. Srikiatkhachorn A, Kasantikul V, Maneesri S, Govitrapong P. Alteration of serotonergic transmission in migraine patients with analgesics abuse headache. In: Proceeding of the Chulalongkorn University 80th Anniversary Research Conference.Bangkok,ChulalongkornUniversity Press 1997;527-38.

  24. Srikiatkhachorn A, Govitrapong P, Kasantikul V. Role of serotonin in vascular headache: The platelet study. In:BunnagSC, Srikiatkhachorn A, Patumraj S. eds. Proceeding of the Third Asian Congress for Microcirculation.Bologna: Manduzzi Editore;1997:151-7.

  25. Srikiatkhachorn A, Maneesri S, Govitrapong P, Kasantikul V. Derangement of serotonin system in migraine patients with analgesics abuse headache: clues from platelets. Headache 1998:38:43-9.

  26. Srikiatkhachorn A, Puangniyom S, Govitrapong P. Plasticity of 5-HT2A serotonin receptor in patients with analgesic-induced transformed migraine. Headache. 1998 Jan;38(1):534-9.

  27. Srikiatkhachorn A, Govitrapong P, Phanthumchinda K.  Role of serotonin in pathogenesis of analgesic-induced headache. In: Boon-Long S, Covavisaruch S, eds. Proceeding of the Sixth CU-af Seminar on “Medical Science Towards the Year 2000.Bangkok,ChulalongkornUniversity 1998; 19-34.

  28. Srikiatkhachorn A, Anuntasethakul S, Patumraj S, Kasantikul V. Can hyposerotonin be the cause of nitric oxide supersensitivity in migraine? Cephalalgia. 1999 May;19(4):342-3.

  29. Srikiatkhachorn A, Tarasub N, Govitrapong P.  Acetaminophen-induced antinociception via central 5-HT2A receptors. Neurochem Int 1999 Jun;34(6):491-8.

  30. Anuntasethakul T, Srikiatkhachorn A, Maneesri S, Patumraj S, Kasantikul V.  Ultrastructural changes in endothelial cells of cerebral microvessels after exposure to nitric oxide donor.  Neuropathology 1999 Sep;19(3):259-66.

  31. Srikiatkhachorn A, Anuntasethakul T, Maneesri S, Phansuwan-Pujito P, Patumraj S, Kasantikul V. Hyposerotonin-induced nitric oxide supersensitivity in the cerebral microcirculation. Headache 2000 Apr;40(4):267-75.

  32. Srikiatkhachorn A, Tarasub N, Govitrapong P. Effect of chronic analgesic exposure on the central serotonin system. A possible mechanism of analgesic abuse headache. Headache 2000 May;40(5):343-50.

  33. Govitrapong P, Chagkutip J, Turakiteanakan W, Srikiatkhahchorn A. Platelet 5-HT2A receptors in schizophrenic patients with and without neuroleptic treatment. Psychiatry Res 2000 Sep 25;96(1):41-50.

  34. Nudmamud S, Siripurkpong P, Chindaduangratana C, Harnyuttanakorn P, Lotrakul P, Laarbboonsarp W, Srikiatkhachorn A, Kotchabhakdi N, Casalotti SO. Stress, anxiety and peripheral benzodiazepine receptor mRNA levels in human lymphocytes. Life Sci 2000 Sep 22;67(18):2221-31.

  35. Srikiatkhachorn A, Anuntasethakul T, Phansuwan-Pujito P, Patumraj S, Kasantikul V. Effect of Serotonin Depletion on Nitric Oxide Induced Cerebrovascular Nociceptive Response. Neuroreport 2001 Apr 17;12:967-71.

  36. Srikiatkhachorn A. Pathophysiology of chronic daily headache. Curr Pain Headache Rep 2001;5:537-44.

  37. Srikiatkhachorn A. Chronic daily headache: A scientist's perspective. Headache. 2002 Jun;42(6):532-7.

  38. Anomasiri W, Sanguanrangsirikul S, Srikiatkhachorn A, Chuntavan P. Changes of immune system in military recruits after the training program. J Med Assoc Thai 2002;85(Suppl 1):327-35.

  39. Srikiatkhachorn A, Suwattanasophon C, Ruangpattanatawee A, Phansuwan-Pujito P,. 5-HT2A receptor activation and nitric oxide synthesis: a possible mechanism determining migraine attacks. Headache 2002;42:566-74.

  40. Srikiatkhachorn A. Chronic daily headache: a scientist’s perspective. Headache 2002;42:532-7 (Review article)

  41. Suwanwela NC, Srikiatkhachorn A, Tangwongchai S, Phanthumchinda K. Cerebral autosomal dominant arteriopathy with subcotical infarcts and leukoencephalopathy (CADASIL) in a Thai family. J Med Assoc Thai 2003 Feb;86(2):178-82

  42. Chucharoen P, Chetsawang B, Srikiatkhachorn A, Govitrapong P. Melatonin receptor expression in rat cerebral artery. Neuroscience Letters. 2013 May 8;241(3)259-61.

  43. Chucharoen P, Chetsawang B, Govitrapong P, Srikiatkhachorn A. Melatonin receptor expression in rat cerebral artery. Neurosci Lett 2003; 341: 259–61.

  44. Srikiatkhachorn A, Maneesri S, Pattamanont J, Patumraj S. Nitric Oxide scavenging may explain the potential antimigraine effect of melatonin. Cephalalgia. 2003 Sep;23(7):645-6.

  45. Pattamanont J, Maneesri S, Patumraj S, Srikiatkhachorn A. Cortical Spreading Depression induces cerebral hypeaemia but not perivascular inflammation. Cephalalgia. 2013 Sep;23(7):649.

  46. Suwattanasophon C, Phansuwan-Pujito P, Srikiatkhachorn A. 5-HT(1B/1D) serotonin receptor agonist attenuates nitroglycerin-evoked nitric oxide synthase expression in trigeminal pathway. Cephalalgia. 2003 Oct;23:825-32.

  47. Kulaputana O, Kaimusik S, Sanguanrangsirikul S,Srikiatkhachorn A, Udayachalerm W. Differences in heart rate variability between endurance and resistance trained athletes. Chula Med J 2003;47:241-254

  48. Maneesri S, Patamanont J, Patumraj S, Srikiatkhachorn A. Cortical spreading depression, meningeal inflammation and trigeminal nociception. Neuroreport 2004 Jul 19;10:1623-7.

  49. Srikiatkhachorn A, Supornsilpchai W, Sanguanrangsirikul S, Maneesri S. Serotonin depletion potentiates the development of cortical spreading depression and enhances the expression of VR1 receptor in trigeminal ganglia. Cephalalgia. 2005 Oct;25(10):861.

  50. Kaewwongse M, Maneesri S, Srikiatkhachorn A. Involvement of 5-HT2A receptor in central sensitization secondary to tissue inflammation. Cephalalgia. 2005 Oct;25(10):883.

  51. Supornsilpchai W, Sanguanrangsirikul S, Maneesri S, Srikiatkhachorn A. Effect of sensitization of trigeminal nociceptive system on development of cortical spreading depression and trigeminal vanilloid receptor expression. Cephalalgia. 2005 Oct;25(10):883.

  52. Supornsilpchai W, Sanguanrangsirikul S, Maneesri S, Srikiatkhachorn A. Serotonin depletion, cortical spreading depression and trigeminal nociception. Headache. 2006 Jan;46:34-39.

  53. Le Grand SM, Patumraj S, Phansuwan-Pujito P, Srikiatkhachorn A. Melatonin inhibits cortical spreading depression-evoked trigeminal nociception. Neuroreport 2006 Nov 6;17(16):1709-13.

  54. Srikiatkhachorn A. Towards the better underastanding about pathogenesis of chronic daily headache. J Med Assoc Thai 2006;89(Suppl 3):S234-43.

  55. Maneepak M, LeGrand SM, Srikiatkhachorn A. NMDA receptor phosphorylation may play role in low serotonin-induced trigeminal nociceptive facilitation. Cephalalgia. 2007 Jun;27(6):603.

  56. LeGrand M, Srikiatkhachorn A, Sanguanrangrisikul S, Supornsilpchai W. Effect of paracetamol on neurovascular response to cortical spreading depression. Cephalalgia. 2007 Jun;27(6):612.

  57. LeGrand S, Nuanboonma P, Srikiatkhachorn A, Sopornsilpchai W. Involvement of NO in the trigeminal nociceptive facilitation induced by serotonin depletion. Cephalalgia. 2007 Jun;27(6):618-9.

  58. LeGrand M, Maneepak M, Sanguanrangrisikul S, Srikiatkhachorn A, Supornsilpchai W. Plasticity of trigeminovascular system in low serotonin condition: the complex changes. Caphalalgia.  2007 Jun;27(6):617.

  59. Chuchareon P, Chetsawang B, Putthaprasert C, Srikiatkhachorn A, Govitrapong P. The presence of melatonin receptors and inhibitory effect of melatonin on hydrogen peroxide-induced endothelial nitric oxide synthase expression in bovine cerebral blood vessels. J Pineal Res. 2007 Aug;43:35-41

  60. Kaewwongse M, le Grand SM, Srikiatkhachorn A. Involvement of 5-HT2A receptor in chronic inflammatory pain. Chula Med J 2007;51:471-81.

  61. Nimnuan C, Srikiatkhachorn A. Is there really a “migraine personality”? Practical Neurology. 2007 July;30-35.

  62. Maneepak M, le Grand SM, Srikiatkhachorn A. Serotonin depletion increases nociception-evoked trigeminal NMDA receptor phosphorylation. Headache 2009 Mar;49:375-82.

  63. Bongsebandhu-phubhakdi S, Phisonkunkasem T, Srikiatkhachorn A. Enhancing effect of nociceptin in cortical spreading depression: electrophysiological study using an animal model of migraine. Asian Biomedicine 2009;3:325-329.

  64. Srikiatkhachorn A, Supornsilpchai W, LeGrand SM. Involvement of pro-nociceptive 5-HT2A receptor in the pathogenesis of medication-overuse headache. Cephalalgia. 2009 Oct;29(SI,SUPPL.1):116.

  65. Supornsilpchai W, le Grand MS, Srikiatkhachorn A. Involvement of pro-nociceptive 5-HT2A receptor in the pathogenesis of medication-overuse headache. Headache 2010 Feb;50:185-197.

  66. Supornsilpchai W, le Grand MS, Srikiatkhachorn A. Cortical hyperexcitability and mechanism of medication-overuse headache. Cephalalgia 2010 Sep;30:1101-1109.

  67. Bongsebandhu-phubhakdi S, Phisolkulkasem T, Srikiatkhachorn A. Modulation of cortical spreading depression and trigeminal nociception by nociceptin/orphanin FQ. Journal of Headache and Pain. 2010 Oct;11(SUPPL.1):S10.

  68. Maneepak M, Bongsebandhu-phubhakdi S, Legrand SM, Srikiatkhachorn A. Multiple cortical spreading depressions impair hippocampal long-term potentiation. Journal of Headache and Pain. 2010 Oct;11(SUPPL.1):S38-9.

  69. Supronsinchai W, Le Grand SM, Srikiatkhachorn A. Chronic paracetamol treatment increases the endothelial cell ultrastructural changes evoked by cortical spreading depression. Journal of Headache and Pain. 2010 Oct;11(SUPPL.1):S89.

  70. Le Grand S, Saengjaroentham C, Supronsilpchai W, Srikiatkhachorn A. The increase in the calcitonin gene-related peptide immunoreactivity following the CSD activation in the serotonin depleted state. Journal of Headache and Pain. 2010 Oct;11(SUPPL.1):S136-7.

  71. Le Grand SM, Supornsilpchai W, Saengjaroentham C, Srikiatkhachorn A. Depletion of serotonin leads to cortical hyperexcitability and trigeminal nociceptive facilitation via nitric oxide pathway.Headache 2011;51:1152-60.

  72. Bongsebandhu-phubhakdi S, Phisonkulkasem T, Srikiatkhachorn A. Nociceptin/Orphanin FQ modulates cortical activity and trigeminal nociception. Headache. 2011 Sep;51:1245-53.

  73. Kalandakanond-Thongsong S, Daendee S, Srikiatkhachorn A. Effect of the acute and chronic estrogen on anxiety in the elevated T-maze. Physiology & Behaviours 2012 Jan 18;105:357–63.

  74. Bongsebandhu-phubhakdi S, Srikiatkhachorn A. Pathophysiology of Medication-overuse Headache: Implications from Animal Studies. Current Pain and Headache Reports. 2012 Feb;16(1):110-5.

  75. Nimnuan C, Asawawichienjinda T, Srikiatkhachorn A Potential risk factors for psychiatric disorders in patients with headache. Headache 2012;52:90-8.

  76. Maneepak M, Srikiatkhachorn A,Bongsebandhu-phubhakdi S. Involvement of AMPA receptors in CSD-induced impairment of LTP in the hippocampus. Headache. 2012 May;52(5):2012.

  77. Saleewong T, Srikiatkhachorn A, Maneepak M, Chonwerayuth A, Bongsebandhu-phubhakdi S. Quantifying altered long-term potentiationin the CA1 hippocampus. J Integrative Neurosci. 2012 Sep;11(3):243-64.

  78. Srikiatkhachorn A, le Grand SM, Supornsilpchai W, Storer RJ. Pathophysiology of Medication Overuse Headache-An Update. Headache, 2013.

  79. Chatchaisak, D., Srikiatkhachorn, A., Grand, S. M. L., Govitrapong, P., & Chetsawang, B. The role of calcitonin gene-related peptide on the increase in transient receptor potential vanilloid-1 levels in trigeminal ganglion and trigeminal nucleus caudalis activation of rat. Journal of Chemical Neuroanatomy, 47, 50-56.

  80. Bongsebandhu-Phubhakdi, S.; Maneepark, M.; Srikiatkhachorn, A. Cortical spreading depression impairs hippocampal long-term potentiation by the alteration of glutamate receptor responses. Journal of Headache and Pain, Feb 2013.

  81. Chatchaisak, D., Chetsawang, B., le Grand, S.M., Govitrapong, P., Srikiatkhachorn, A. Role of TRPV-1 in CGRP-mediated trigeminal sensitization. Journal of Headache and Pain, Feb 2013.

  82. Saleewong, T., Srikiatkhachorn, A., Maneepark, M., Chonwerayuth, A., & Bongsebandhu-Phubhakdi, S. (2013). Computational approach to long-term potentiation in hippocampal CA1 area describes the efficacy of stimulation patterns. Asian Biomedicine. 2013, 7(3), 347-356.

  83. Srikiatkhachorn A, Le Grand SM, Supornsilpchai W, Storer RJ. Pathophysiology of medication overuse headache - An update. Headache. 2014 Jan;54(1):204-10.
  84. Vibulyaseck S, Bongsebandhu-Phubhakdi S, Le Grand SM, Srikiatkhachorn A. Potential risk of dihydroergotamine causing medication-overuse headache: preclinical evidence. Asian Biomedicine. 2014 Jun;8(3):323-31.

  85. Yisarakun W, Supornsilpchai W, Chantong C, Srikiatkhachorn A, Maneesri-le Grand S. Chronic paracetamol treatment increases alterations in cerebral vessels in cortical spreading depression model. Microvascular Research. 2014 Jul;94:36-46.

  86. Chatchaisaka D, Connor M, Srikiatkhachorn A, Chetsawang B.The potentiate effect of CGRP on TRPV1 activity in rat trigeminal neurons. Journal of Neurochemistry. 2014 Aug;130(SUPP1):65-6.

  87. Storer RJ, Supronsinchai W, Srikiatkhachorn A. Animal Models of Chronic Migraine. Current Pain and Headache Reports. 2015;19(1).

  88. Saengjaroentham C, Supornsilpchai W, Ji-au W, Srikiatkhachorn A, Maneesri-le Grand S. Serotonin depletion can enhance the cerebrovascular responses induced by cortical spreading depression via the nitric oxide pathway. International Journal of Neuroscience. 2015;125(2):130-9.

  89. Supronsinchai W, Srikiatkhachorn A. Modulate the nucleus raphe magnusincrease cortical excitability and cortical blood flow. Cephalalgia. 2015;35:232-.

  90. Srikiatkhachorn A, le Grand SM, Suprinsinchai W. Serotonin depletion and plasticity of trigeminovascular system. Cephalalgia. 2015;35:225-.

  91. Saleeon W, Jansri U, Srikiatkhachorn A, Bongsebandhu-phubhakdi S. Estrous Cycle Induces Peripheral Sensitization in Trigeminal Ganglion Neurons: An Animal Model of Menstrual Migraine. J Med Assoc Thai 2016;99(2):206-212.

  •  Chapters and Text:

  1. Srikiatkhachorn A, Hemachuda T.  Tetanus. Medlink Neurology, New York: Arbor 1994 to present

  2. Srikiatkhachorn A, Jongwutiwes S, Phanthumchinda K. Trichinosis. Medlink Neurology, New York: Arbor Publishing 1999 to present

  3. Nimnuan C, Srikiatkhachorn A. Psychiatric comorbidity of migraine. Medlink Neurology, New York: Arbor Publishing 2005 to present

  4. Srikiatkhachorn A. Chronics Daily Headache. In: Pappagallo M (editor). The Neurological Basis of Pain.New York: McGraw-Hill Publishing, 2005: 376-390

  5. Nimnuan C, Srikiatkhachorn A. Epidemiology of headache. Medlink Neurology,  New York: Arbor Publishing 2010 to present 

 

รางวัลที่ได้รับ:

  • 2551 รางวัลเมธีวิจัยอาวุโส สำนักงานกองทุนสนับสนุนการวิจัย (สกว.) ประจำปี 2551
© 1947-2015 Department of Physiology, Faculty of Medicine, Chulalongkorn University, All right reserved.
Professional Joomla Templates - 888 Poker Review